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Neutrophil-to-Lymphocyte & Platelet-to-Lymphocyte Ratios

Inflammation ratios from absolute neutrophil, lymphocyte and platelet counts.

For healthcare professionalsHematologyv1.0.1

For healthcare professionals / clinical use. Not a self-diagnosis tool.

Your measurements

×10⁹/L
×10⁹/L
×10⁹/L

Calculated on your device. Nothing is sent to a server.

Your result will appear here

Enter your measurements, then press Calculate.

Methodology

NLR (Zahorec 2001); PLR

NLR = neutrophils ÷ lymphocytes; PLR = platelets ÷ lymphocytes

Research markers of systemic inflammation. Cut-offs vary widely between studies and conditions, so none is applied.

Who it is for
Adults.
Version
1.0.1

How this calculator works

Where the formula comes from

  • Zahorec (2001) followed white cell counts in 90 oncology ICU patients and proposed the neutrophil-to-lymphocyte ratio as a simple marker of stress and systemic inflammation; its prognostic value was to be tested in further studies.[1]

The inputs

  • In that study, more severe illness (SOFA and APACHE II) went with more marked neutrophilia and lymphocytopenia.[1]

Where accuracy falls (published evidence)

  • In 413 healthy working adults, normal NLR values ranged from 0.78 to 3.53 (mean 1.65).[2]

Sources

  1. Zahorec R. Ratio of neutrophil to lymphocyte counts—rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5–14. PMID 11723675
  2. Forget P, Khalifa C, Defour JP, et al. What is the normal value of the neutrophil-to-lymphocyte ratio? BMC Res Notes. 2017;10(1):12. doi:10.1186/s13104-016-2335-5

Compiled from the published sources above. Every statement was agreed independently by three AI research tools (Claude, ChatGPT, DeepSeek) and its source verified in PubMed or Crossref by the Hakeemly editorial team. Not reviewed by a doctor unless stated. Agreed on

Worked example: how to calculate NLR / PLR

Inputs

Absolute neutrophils
4 ×10⁹/L
Absolute lymphocytes
2 ×10⁹/L
Platelets (optional)
250 ×10⁹/L

Result

Neutrophil-to-lymphocyte ratio
2
Platelet-to-lymphocyte ratio
125

An illustration with sample values, worked out with the same method the tool above uses.

Limitations

  • Not diagnostic; affected by steroids, infection, chemotherapy and stress.
  • In healthy adults, normal values ranged from about 0.78 to 3.53 (Forget 2017).

References

  1. Zahorec R. Ratio of neutrophil to lymphocyte counts—rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5–14.
  2. Forget P, Khalifa C, Defour JP, et al. What is the normal value of the neutrophil-to-lymphocyte ratio? BMC Res Notes. 2017;10(1):12. doi:10.1186/s13104-016-2335-5

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